point mutation

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Word: Point Mutation

Part of Speech: Noun

Definition: A point mutation is a change in a single base (or "point") in the DNA sequence of a gene. This change can happen in several ways, such as when one base is replaced by another. It can affect how a gene works, which can lead to changes in traits or sometimes cause diseases.

Usage Instructions:

• When you use "point mutation," you are usually talking about genetics or biology.
• It is important to use it in contexts related to DNA, genes, and heredity.

Example Sentence:

• "The scientist discovered a point mutation in the gene that was responsible for the patient's condition."

Advanced Usage:

• Point mutations can be classified into three types:
  • Silent Mutation: The change does not affect the protein made by the gene.
  • Missense Mutation: The change results in a different amino acid being produced in the protein, which can affect its function.
  • Nonsense Mutation: The change creates a stop signal in the protein sequence, which can lead to a nonfunctional protein.

Word Variants:

• Point Mutations (plural): Refers to more than one instance of point mutations.
• Mutate (verb): To undergo a change, especially in genetic material.
• Mutation (noun): The act or process of changing or the result of such a change.

Different Meanings:

• Outside of genetics, "point" can refer to a specific location, time, or matter in discussions (e.g., "the main point of the argument").
• "Mutation" can also refer to general changes or alterations in various contexts, not just biological.

Synonyms:

• Genetic alteration
• Sequence change
• Base substitution (specific type of point mutation)

Idioms and Phrasal Verbs:

• There are no specific idioms or phrasal verbs that directly relate to "point mutation," but in discussions about genetics, you might encounter phrases like "turn over a new leaf" (change in behavior) or "change gears" (shift focus), though these are metaphorical and not directly linked to mutations.

Summary:

A point mutation is an important concept in genetics, describing a small but significant change in the DNA sequence that can have various effects on an organism.

Academic

Noun

1. (genetics) a mutation due to an intramolecular reorganization of a gene

Synonyms

• gene mutation